In this talk, some aspects of the effective, or collective, description of complex quantum systems within the path integral formalism are described. In general, considering a generalisation of the standard Feynman-Vernon Caldeira-Leggett model, an effective theory is obtained after "integrating out" the environment. Depending on the environment and the choice of coupling, a quantum theory of dissipation, or a coordinate-dependent mass can be obtained. For the latter case, the proper discretisation of the path integral is essential: we find that in general a simple effective low-energy Hamiltonian, in which only the coordinate-dependent mass enters, cannot be formulated. The quantum theory of weakly coupled superconductors and the quantum dynamics of vortices in Josephson junction arrays are examples where these considerations, in principle, are of relevance.