Statistical Physics and Quantitative Biology
University of Cologne
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Physics of Nonequilibrium and Disorder

An important subject of modern statistical physics and a focus of our work are systems away from normal thermodynamic equilibrium, such as growth phenomena and `frozen' disordered materials. These systems are ubiquitous in nature, and they are a challenge for the theorist since traditional methods often fail. Our past work in this area has focused on nonperturbative aspects of surface growth and turbulence. Nonequilibrium statistical mechanics is also crucial for a quantitative understanding of biological evolution and enters much of our current work. Recently, we have proved a fluctuation theorem for stochastic evolutionary processes of biological systems.

Selected physics publications
Dynamical anomalies and intermittency in Burgers turbulence
M. Lässig, Phys. Rev. Lett. 84, 2618, (2000)
Quantized scaling of growing surfaces
M. Lässig, Phys Rev. Lett. 80, 2366 (1998)
On the renormalization of the Kardar-Parisi-Zhang equation
M. Lässig, Nucl. Phys. B448, 559, (1995)
Selected applications to biology and bioinformatics
Significance analysis and statistical mechanics: an application to clustering
M. Luksza, M. Lässig, and J. Berg, Phys. Rev. Lett. 105, 220601 (4 pages), (2010)
Fitness flux and ubiquity of adaptive evolution
V. Mustonen and M. Lässig, Proc. Natl. Acad. Sci. 107, 4248-53, (2010)
Molecular evolution under fitness fluctuations
V. Mustonen and M. Lässig, Phys Rev Lett. 100, 108101, (2008)
Similarity detection and localization
T. Hwa and M. Lässig, Phys. Rev. Lett. 76, 2591, (1996)

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